Prevalence of M-proteins in serum of hospitalized patients. Physicians' response to finding M-proteins in serum protein electrophoresis.

نویسنده

  • A O Vladutiu
چکیده

M-proteins (tall, narrow spikes) are the major finding in serum protein electrophoresis (SPE), and their presence could signify lymphoproliferative diseases. The physicians' response to this finding in 73,630 patients in whom a SPE was performed as part of a routine screening at hospital admission was studied. Serum and urine immunoelectrophoresis (IEP) were requested on the report of SPE in all patients who showed M-proteins on SPE. In 59 percent of these patients, neither serum nor urine IEP were ordered, and it was assumed that the results of SPE were ignored by physicians. The frequency of M-proteins (1.1 percent) in the hospitalized patients was higher than that reported for normal individuals. It is suggested that SPE should not be performed as a screening test in hospitals.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

الگوی الکتروفورز پروتئین های سرم در انواع مختلف سرطان مشابه فاز حاد است

Background and purpose : The levels of serum acute phase reactant proteins change in different malignant diseases that along with other proteins could be assessed by electrophoresis. Materials and methods: The electrophoretic pattern of serum proteins of 85 patients bearing different types of neoplasia and 85 matched normal adults were comparatively studied by agarose gel electrophoresis t...

متن کامل

A distinct serum protein pattern in patients with paranoid schizophrenia

Introduction: Schizophrenia is a chronic mental illness, whose aetiology is still unclear; therefore, information about differences in serum protein patterns may improve the understanding of the pathophysiology of schizophrenia. The goal of this study was to use the proteomic approach to identify altered protein levels in the serum samples from patients with schizophrenia. Methods: Blood wa...

متن کامل

Monoclonal Gammopathy of Undetermined Significance with Metastatic Carcinoma – A Rare Presentation

The presence of a low level of M protein in the peripheral blood <3gm/dl which is below the required cut off for the diagnosis of plasma cell myeloma is known as monoclonal gammopathy of undetermined significance (MGUS). Elevated levels of serum M protein and detection of M band on serum protein electrophoresis (SPE) can occur in chronic diseases not related to B cell disorders and not always d...

متن کامل

Effect of water salinity on total protein and electrophoretic pattern of serum proteins of grass carp, Ctenopharyngodon idella

In this study the effects of water salinity on serum total protein and its components in grass carp were investigated. The aim of this study was to determine the effect of salinity tolerance of fish on total serum protein level and its components as an indicator of liver and kidney activity. One hundred and twenty grass carp were divided into four groups, randomly. The first three groups were r...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Annals of clinical and laboratory science

دوره 17 3  شماره 

صفحات  -

تاریخ انتشار 1987